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If the patient is allergic to zoledronic acid, another bisphosphonate (the group of substances to which Zoledronic acid Actavis belongs), or any of the other ingredients of this medicine (listed in Description).
If the patient is breast-feeding.
Zoledronic acid Actavis is contraindicated in patients with creatinine clearance <35 mL/min and in those with evidence of acute renal impairment due to an increased risk of renal failure.
